Ablation of Fgfr3 in mice causes the expansion of proliferating and hypertrophic chondrocytes, whereas in humans, loss-of-function pathogenic variants in the FGFR3 gene could cause the camptodactyly, tall stature, scoliosis, and hearing loss (CATSHL) syndrome [101,102,103]. Here, FGFR3 is linked to hearing loss disorder.