ACE inhibitors are essential in the treatment for both high and low risk hypertension, and combination therapies such as “polypill” incorporate ACE inhibitors (enalapril) along with non-steroidal anti-inflammatory drugs (NSAID; aspirin), statins (atorvastatin) and diuretics (hydrochlorothiazide) [4,5]. Here, ACE is linked to Hypertension.