Interestingly, the protein levels of Cleaved-caspase-1 of the T2DM mice were significantly suppressed compared with that in the control group, while surfactin treatment significantly increased the Cleaved-caspase-1/caspase-1 ratio but did not alter Cleaved-caspase-1 levels compared with that in the T2DM group; this trend is similar to the control group (Figure S2B,C). The gene discussed is CASP1; the disease is type 2 diabetes mellitus.