STAT3 and hepatocellular carcinoma: Ectopically expressed STAT3 rescued cells from sorafenib-triggered ferroptotic cell death (Figure 4A), restored cystine uptake (Figure 4B) and total GSH levels (Figure 4C), decreased lipid ROS levels (Figure 4D), and reduced lipid peroxidation (Figure 4E) in HCC cells treated with sorafenib.