In this interaction, recognition of M. loti R7A NF by plant receptors (NFR1 and NFR5) triggers a regulatory cascade leading to the early steps of infection and nodule development, including the expression of EPR3, which functions as an EPS receptor that works in different steps of the symbiotic interaction, so that EPS recognition is reiterated along the nodulation process. This evidence concerns the gene NFASC and infection.