Next, we verified the influence of additional major cardiovascular risk factors like the inflammatory mediator hsCRP (Figure 4A), diabetes (Figure 4B), eGFR (Figure 4C) and arterial hypertension (Figure 4D) on platelet CXCL16–CXCR6 axis as compared to serum sCXCL16. The gene discussed is CXCL16; the disease is diabetes mellitus.