HIF1A and breast carcinoma: The nuclear translocation and transcriptional activity of hypoxia-inducible factor-1α (HIF-1α) were reduced by baicalein, which contributed to the downregulation of HIF-1α–mediated glycolysis uptake and recovered the number and shape of mitochondria as well as their ability to generate ROS, and thus re-sensitized breast cancer cells to TAM treatment [103].