In addition to CaMKI (at Thr177 in CaMKIα [26]) and CaMKIV (at Thr196 in mouse CaMKIV [19,25]), PKB/Akt is phosphorylated at Thr308 and is activated by CaMKKα/1 in NG108 neuroblastoma cells [27] and LNCaP prostate cancer cells [80], thereby protecting the cells from apoptosis (Table 1 and Figure 3). This evidence concerns the gene AKT1 and Familial prostate cancer.