CD86 and viral infectious disease: Figure 10 shows that there was no evidence of DC-SIGN, MMR or CD86 expression in any mock, WT or Δβ2.7 infected monocytes, despite them staining clearly as expected in the differentiated positive controls. We observed low levels of HLA-DR on undifferentiated monocytes, and this increased somewhat on differentiated cells (Figure 10). Interestingly, cells that were infected (GFP-positive) showed lower HLA-DR levels with both WT and Δβ2.7 virus infection. This was not unexpected as both latent and lytic HCMV are known to downregulate HLA-DR to avoid immune recognition [50,51,52].