WNK2 and cancer: Wu et al. observed that the FGFR inhibitor-mediated blockade of the mitogen-activated protein kinase (MAPK)/extracellular-signal-regulated kinase (ERK) pathway in cancer-associated fibroblasts leads to diminished proliferation, migration and secretion of the vascular adhesion molecule 1 (VCAM-1) in these cells, which promotes T cell infiltration by breaking down the tumor/stroma barrier [62].