CD274 and colorectal cancer: It was demonstrated that FGFR2 is able to induce expression of programmed cell death 1 ligand 1 (PD-L1) via the janus kinase (JAK)/STAT pathway in colorectal cancer [55] and a non-T-cell-inflamed phenotype was observed in FGFR3-driven urothelial cancer [56,57], although a recent study from Denmark could not confirm this finding [58].