NCR3 and cancer: Patient prognoses in some cancer types has been found also to be associated with the expression of the activating NK receptor Nkp30 isoforms; while expression of the activating isoforms 1/2 is associated with better patient prognosis, the immunosuppressive NKp30 isoform 3 constitutes a negative prognostic marker for gastrointestinal tumors [26] and high-risk neuroblastoma [27].