The genes controlled by SOX2, UBTF, NFE2L2, TCF3 and STAT3 (Figure 5) are involved in the processes of EMT, the regulation of mesenchymal stem cell differentiation, the invasion and migration of GBM and others (Figure 6), while MYC/MAX-dependent downregulated genes (Figure 7) are involved in translation, focal adhesion apical junction and other processes summarized in Figure 8. The gene discussed is SOX2; the disease is glioblastoma.