We assessed AT inflammation by measuring the mRNA expression of soluble markers of inflammation associated with obesity (adiponectin, leptin, IL-6, TNF-α, MCP-1, CX3CL1, and CCL5) or viral infections (Mx1, CXCL10, and interferon-gamma (γ-IFN)). Here, CCL2 is linked to obesity due to melanocortin 4 receptor deficiency.