SMARCA5 is an ISWI chromatin remodeling ATPase that belongs to the ATP-dependent chromatin remodeling complex SWI/SNF family [35,36], and is involved in tumor proliferation, invasion, chemoresistance, and progression, primarily through chromatin remodeling in DNA damage regions [37,38,39,40,41]. This evidence concerns the gene SMARCA5 and neoplasm.