Furthermore, circSMARCA5 also regulated Vascular Endothelial Growth Factor A (VEGFA) through binding to SRSF1, inhibited angiogenesis by regulating the proportion of angiogenic and antiangiogenic vascular endothelial growth factor subtypes [59], thus acting as an anti-angiogenic molecule for the inhibition of tumor. This evidence concerns the gene SRSF1 and neoplasm.