Modulating Th2 response due to the expression of IL4R, IL4I1, CCL17, CCL22 and BCL2L1 genes.In human and mouse non- small cell lung cancers, the mregDC program is expressed by canonical DC1s and DC2s upon uptake of tumor antigens. The role of this new subset is still under exploration both in homeostatic and pathological conditions. The gene discussed is IL4R; the disease is non-small cell lung carcinoma.