SQSTM1 and breast cancer: On the other hand, overexpression of miR-20a, induced by mycobacterial infection, inhibits the autophagy process in macrophages by targeting ATG7 and ATG16L1 and suppressing their expression [64]; miR-20a is also overexpressed in breast cancer, where it targets several genes related to autophagy, such as BECN1, ATG16L1, and SQSTM1/p62, downregulating them.