Spearman’s rank test showed no significant correlation of TET genes with global 5-hmC levels in PN tissues (Figure 1f–h), while it showed a significant positive correlation of TET1 (r = 0.544, p = 0.05) (Figure 1i) and TET3 (r = 0.5662, p = 0.0437) (Figure 1k) genes with the global loss of 5-hmC in breast cancer but not with the TET2 gene (Figure 1j). Here, TET3 is linked to breast cancer.