PIEZO1 and central nervous system cancer: Using bioinformatics analysis based on the Chinese Glioma Genome Atlas (CGGA) dataset and the Cancer Genome Atlas (TCGA) network, Zhou et al. showed that Piezo1 is positively correlated with phosphatidylinositol-3-OH kinase (PI3K) and AKT2, which play important roles in regulating various cellular functions, such as growth, proliferation, and protein synthesis [33].