Elevated MARCKS phosphorylation enhances migration and invasion of lung cancer cells in vitro and metastasis in vivo [9], while a MARCKS-inhibiting peptide attenuates cell growth, migration, and invasion and reduces metastasis in both subcutaneous and orthotopic xenograft models, likely through modulating NF-κB signaling [42,43,44]. Here, MARCKS is linked to lung cancer.