Cluster marker genes were consistent with the published cell type-enriched genes, including the homeostatic microglia clusters 0, 1, 4, 6 and 22 (P2ry12 and Hexb), tumor-associated microglia clusters 2, 8, 9, 10 (Cd74 and Apoe), monocyte and macrophage clusters 3, 8, 11 (Ly6c2 and Tgfbi), T cell clusters 5, 13, 18, 19, 21 (Cd3d and Trbc2) and NK cluster 7 (Ncr1 and Klra4) (Figure 1e). The gene discussed is APOE; the disease is neoplasm.