Differentially expressed genes (DEGs) in the metastatic tumors were associated with the cell adhesion, including periostin (Postn), cadherin 15 (Cdh15), and dermatopontin (Dpt), as well as angiogenesis-related signaling and regulation of biological quality as the nodes were notably larger in the network. This evidence concerns the gene CDH15 and metastatic neoplasm.