AR and posterior cortical atrophy: In 2022, Ghildiyal et al. discovered a type of LncRNA named NXTAR with the ability to inhibit drug resistance in PCa, and reported that NXTAR directly bound to AR upstream of the AR promoter to enhance EZH2 recruitment, leading to the down-regulation of the AR and AR-V7 expression and positive feedback to increase NXTAR expression [131].