S1PR1 and ovarian cancer: Genes expressed in lymphovascular cells and/or involved in angiogenesis, including SPARC related modular calcium binding-1 (Smoc1) [68,69], matrix GLA protein (Mgp) [70,71], angiopoietin 2 (Angpt2) [72,73], VEGFRs co-receptor neuropilin-2 (Nrp2) [74], and sphingosine-1-phosphate receptor 1 (S1pr1) [75] were also significantly upregulated in FOXC2-expressing ovarian cancer cells (Figure 4A).