FOXC2 is known to aid in tumor progression by promoting epithelial-mesenchymal transition (EMT) [19,21,22,32,33], stem cell differentiation [26,34], proliferation and migration [18,28,30], drug resistance [20,23,24], and resistance to anoikis, a form of programmed cell death that occurs when cells detach from the extracellular matrix [26]. The gene discussed is FOXC2; the disease is neoplasm.