Furthermore, the multivariable Cox regression analysis adjusting for tumor size, grade, Ki67, ER, PR, HER2, and tamoxifen showed that CD19, IMMUNE1, and PD-L1 remained significant prognostic factors among all the patients (Table 5) and for the ER+/HER2− patients (adjusting for tumor size, grade, Ki67, and tamoxifen). This evidence concerns the gene ESR1 and neoplasm.