Some miRNAs, such as let-7 [115], miR-18a* [116], miR-30b [117], miR-143 [118] and miR-145 [119], have been shown to be tumor suppressors (since they inhibit KRAS expression) and potential biomarkers for predicting favorable responses to anti-EGFR therapy. This evidence concerns the gene KRAS and neoplasm.