The resulting Y3.3UVR clones were selected for immune reactivity by assessing the proliferation of syngeneic CD8 T cells labeled with a cell division tracker and co-cultured with syngeneic bone-marrow-derived dendritic cells pulsed with tumor cell lysates (Figure 1b,c), and also tested for IFNγ-mediated induction of MHC-I expression (Figure 1a). Here, CD8A is linked to neoplasm.