Thus, incorporating other genotypic information as well as advanced MR sequences, such as diffusion-weighted and perfusion-weighted imaging, which can provide cellularity and angiogenesis for tumor characteristics in gliomas [31,34,35], may aid in the discovery of “strong” imaging features with higher correlations than conventional MR sequences to improve the predictive power of MGMT methylation [36]. This evidence concerns the gene MGMT and neoplasm.