A number of the identified transporters (e.g., SLC22A12/URAT1, SLC22A6/OAT1, SLC22A8/OAT3, ABCG2) are well-established uric acid transporters; this may be clinically important since, as discussed above, a number of studies indicate that altered uric acid levels and kidney cancer are associated. Here, SLC22A8 is linked to kidney cancer.