The major target proteins and signaling pathways of PAK1 are introduced to regulate gastric cancer cell proliferation (MORC2 [110], Smad2/3 [111]), migration, metastasis and invasion (ATF2/miR-132 [112], RUFY3 [113]) and cell cycle processes (CyclinD1 [114], Cyclin B [115]). This evidence concerns the gene PAK1 and gastric cancer.