For example, circ-ITCH inhibits TC progression by sponging miR-22-3p and upregulating CBL level [71]; circ_0025033 accelerates TC proliferation through sponging miR-1233, and miR-1304 [48]; circ_0005273 acts as an oncogene through targeting miR-1138 [64]; circITGA7 acts as miR-198 ceRNA to regulate FGFR1 expression [72]; and overexpression of circular RNA circ-NEK6 abrogates the tumor suppressive effect of miR-370-3p on TC via the WNT signaling pathway [73]. This evidence concerns the gene FGFR1 and neoplasm.