Additionally, we observed that LETM2 expression correlated with tumor inflammation signature (R = -0.15, p = 0.047), PI3K-AKT-mTOR pathway (R = −0.21, p = 0.006), and P53 pathway (R = 0.25, p = 0.001) (Figure 2D–F, Figure S1). Here, AKT1 is linked to neoplasm.