To further clarify the mechanisms by which Fasudil inhibits the survival and expansion of EGFR-resistant-mutations NSCLC cells, we performed RNA-seq analyses involving H1975 cells to identify subsets of sensitive genes resulting from Fasudil treatment (the DEGs were defined as log expression fold changes, |logFC| > 1, with p < 0.05). The gene discussed is EGFR; the disease is non-small cell lung carcinoma.