MYC is an essential molecular hub in CML pathophysiology [40] and could actively participate in the dysregulation of PTBP1 and hnRNPA1 as well as PRMT5 and SRSF1, genes deregulated by MYC in other cancers [39]. The gene discussed is HNRNPA1; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.