Our results further suggest that besides LTF AML and CML cells differ in the expression of genes encoding other proteins with antimicrobial activity as part of the innate and humoral immune system, namely, cathelicidin antimicrobial peptide (CAMP), which is cleaved into a potent antimicrobial peptide LL-37, arginase 1 (ARG1), peptidoglycan recognition protein (PGLYRP1) and calcium-binding protein S100A12. Here, PGLYRP1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.