Here, we show that AML and CML differ in the expression of a set of genes including golgi brefeldin A resistant guanine nucleotide exchange factor 1 (GBF1), membrane glycoprotein CD177, haptoglobin (HP), haptoglobin-related protein (HPR), proteoglycan 3, pro eosinophil major basic protein 2 (PRG3) and apoptosis antagonizing transcription factor (AATF). The gene discussed is AATF; the disease is acute myeloid leukemia.