To define a clinical relevance for the relationship between IL6/LIF expression and response to AET, we examined the expression of ERα, IL6 and LIF in tumor specimens derived from a cohort of patients with ovarian, Fallopian tube or primary peritoneal cancer treated with AET (Figure 1A) [4] and assessed the correlations between expression patterns and PFI. This evidence concerns the gene ESR1 and neoplasm.