Compared with normal tissues, IGF2BP2, HNRNPC, YTHDF1, HNRNPA2B1, KIAA1429, RBM15, ELAVL1, FMR1, METTL3, IGF2BP3, HNRNPG, WTAP, IGF2BP1, METTL16, YTHDF2, CBLL1, ALKBH5, YTHDF3, METTL14, FTO, YTHDC1 were highly expressed in HNSCC tissues. Here, METTL16 is linked to head and neck squamous cell carcinoma.