By analyzing the expression differences of 5 m6A-related eRNAs in 43 pairs of samples from the TCGA-HNSCC cohort and 20 pairs of HNSCC samples from our hospital, we found that compared with normal tissues, the protective gene LINC00271 was lowly expressed in HNSCC samples, the protective gene MIAT was highly expressed in HNSCC samples due to compensatory elevation, and MIR4435-2HG was highly expressed as a risk gene in HNSCC samples (Figure 7A,B). Here, MIAT is linked to head and neck squamous cell carcinoma.