GLP1R and steatosis: In a recent in vitro model of steatotic HepG2 cells, results demonstrated that Ex-4-induced the activation of GLP-1R, and reduced oleic acid-mediated steatosis in HepG2 cells by attenuating fatty acid uptake and transport via fatty acid-binding protein-1 gene downregulation, while the effect of Ex-4 was found to be Wnt/β-catenin pathway-dependent [31].