CircMET (hsa_circ_0082002), which is highly expressed in HCC tissue and exosomes compared to non-tumor cells, promotes HCC cells’ survival by acting on the miR-30-5p/Snail/dipeptidyl peptidase 4 (DPP4)/CXCL10 axis, with the consequent inhibition of CD8 T cell functions and a resistance to anti-PD-1 therapy [138]. This evidence concerns the gene CD8A and hepatocellular carcinoma.