ASGR1 and hepatocellular carcinoma: AnnexinV+ EpCAM+ Human Asialoglycoprotein Receptor 1 (ASGPR1+) MVs were able to distinguish patients with cirrhosis and liver cancer (HCC or cholangiocarcinoma) from those with no malignancy, and this was confirmed by the drop in the concentration 7 days after curative resection [119].