To better mirror the characteristics of HCC, the GRIm-Score was implemented with other circulating markers that resulted independent prognostic factors of survival in a multivariate analysis; therefore, the HCC-GRIm-Score was obtained, including albumin (<35 g/L = 1), LDH (>245 U/L = 1), NLR (≥4.8 = 1), Aspartate Aminotransferase to Alanine Aminotransferase AST-to-ALT ratio (≥1.44 = 1), and total bilirubin (≥22.6 umol/L = 1). Here, GPT is linked to hepatocellular carcinoma.