PDCD1 and hepatocellular carcinoma: The first trial of the anti-TIM3 antibody LY3321367 in combination with an anti-PD1 agent (NCT03099109) was stopped due to unspecified reasons [78], while a second trial investigating a different anti-PD1/anti-TIM3 combination (dostarlimab + cobolimab) in HCC patients is still ongoing (NCT03680508).