KDR and adrenocortical insufficiency: A total of 9649 reports of adrenal hypofunctions were found (mainly AI, N = 6402); in 314 cases, at least one VEGFR-TKI was reported (3.25% of total adrenal hypofunction reports in FAERS, and 0.21% within VEGFR-TKIs), especially cabozantinib (74), lenvatinib (67), sunitinib (62), axitinib (58), lenvatinib (39), pazopanib (26), sorafenib (22), and nintedanib (10).