In addition, TAMs can be divided into two lymphocyte populations: M1-like, which represents the tumor-suppressing activity by producing cytokines such as IL-1, IL-6, IL-23, IFN-α, IL-12 which activate cytotoxic T lymphocytes and NK cells to completely remove tumor cells, or M2-like, which leads to tumor promotion. The gene discussed is IL6; the disease is neoplasm.