VIM and esophageal squamous cell carcinoma: MicroRNA146a, which targets vimentin, has been found to repress the tumor progression in esophageal squamous cell carcinoma (ESCC), and when MiRNA146a is repressed, ESCC mobility is increased through the expression of the mesenchymal marker vimentin, showing the regulatory effect of MiRNA146a on vimentin [74].