More globally, it was shown that several soluble factors secreted when cancer cells undergo Epithelial-to-Mesenchymal Transition, including InterLeukins IL-6 and IL-8, and GM-CSF (Granulocyte-Macrophage Colony Stimulating Factor), stimulate angiogenesis and the recruitment of myeloid cells [18]. Here, CXCL8 is linked to cancer.