Some genes during starvation contribute to antibiotic biosynthesis (dao.1, acat2, acadm, aldh9a1b, fntb, gapdh, hadh, idh1, idh2, pklr, zmpste24) pathways which is in agreement with previous findings [54] demonstrating that short-term starvation prior to infection could be beneficial in obtaining better capability to battle against some infections in red sea bream [54]. The gene discussed is PKLR; the disease is infection.