However, these results are consistent with research showing IL-6 and TNF-α are associated with numerous morbid conditions, such as insulin resistance, cardiac disease, cancer, and others in humans [29,30,31,32,33,34,35,36,37,38,39,40,63,64], and acute abdominal disease (colic) in horses [65]. The gene discussed is TNF; the disease is Insulin resistance.