NFKB1 and acute pancreatitis: After JTE-013 administration, these was a significant reduction in the number of Ly6G + neutrophils and CD68 + macrophages in the pancreas (Fig. 2I, J. Western blotting also suggested that JTE-013 administration reversed the increase in NF-κB p65 protein expression in acute pancreatitis (Fig. 2H).