In bladder cancer, it has been shown that hsa-miR-130b-3p could inhibit the expression of the PTEN gene, that which promotes proliferation, migration, invasion and rearrangement of the cytoskeleton by activating the pathway signaling PI3K; these same authors propose that the inhibition of this miRNA could induce cell apostosis [31]. This evidence concerns the gene PTEN and urinary bladder carcinoma.