Furthermore, the assessment of epigenetic marks in these regions reveled an enrichment of the repressive mark H3K27me3 at the promoter of Bcl2 gene in mature T-ALL, whereas enrichment of active H3K27ac and H3K4m3 marks were more prominent in the Zeb2Tg ETP-ALL. The gene discussed is BCL2; the disease is acute lymphoblastic leukemia.