To further validate these observations in Zeb2Tg ETP-ALL cells, we first examined ZEB2, LSD1, HDAC1 and STAT5b binding using the ENCODE Candidate Cis-Regulatory Elements (cCREs) [24] associated with the Bcl2, Bcl2l11 (BIM) and Hbg1 loci (the latter being a control gene) by using ChIP-qPCR (Fig. S5B). Here, ZEB2 is linked to acute lymphoblastic leukemia.