TLR2 and infection: Next, we then assessed the survival of C. neoformans Δsgl1-vaccinated and unvaccinated C57BL/6 or TLR2−/− mice against a WT challenge, and we found that vaccinated TLR2−/− mice fully succumbed to fatal WT infection at a similar rate to unvaccinated TLR2−/− mice (Fig. 7).