Prostate ICC/IDC CAFÉ CAF shared select marker genes (ASPN and FAP) with extracellular matrix-myofibroblastic CAF (ecm-myCAF), an immunosuppressive CAF subtype detected in breast cancer and shown to be enriched in melanoma and non-small cell lung cancers (NSCLC) that did not respond to anti-PD-1 immunotherapies58. The gene discussed is PDCD1; the disease is melanoma.